Month: February 2018

IT Security Whitepaper

Easy-to-use audit and tracking capabilities Since Leica Microsystems’ instruments are connected to our customer’s networks, the end-customers also need to be assured that the remote service solution supports their security model, provides granular control over user access, and offers easy-to-use audit and tracking capabilities. Source link

I Deleted My Favorite Pictures

It’s impossible to view your own work objectively. When you look at your pictures, you remember the movement, sound, and emotion from the experience. Sometimes, you have to trust others to judge your work. Get an awesome portfolio! http://squarespace.com/tony, coupon code ‘portfolio’ You can watch this podcast on YouTube at http://sdp.io/idmfp Source link

Expression Analysis of Platelet‐derived Growth Factor Receptor Alpha and its Ligands in the Developing Mouse Lung

Activation of the platelet‐derived growth factor receptor‐α (PDGFR α) signaling pathway is critically important during lung alveogenesis, the process in lung development during which alveoli are formed from the terminal alveolar sacs. Several studies have aimed to characterize the expression patterns of PDGFR αand its two ligands (PDGF‐A and ‐C) in the lung, but published analyses have been limited …

Expression Analysis of Platelet‐derived Growth Factor Receptor Alpha and its Ligands in the Developing Mouse Lung Read More »

Basal Body Positioning and Anchoring in the Multiciliated Cell Paramecium Tetraurelia: Roles of OFD1 and VFL3

The development of a ciliary axoneme requires the correct docking of the basal body at cytoplasmic vesicles or plasma membrane. In the multiciliated cell Paramecium, three conserved proteins, FOR20, Centrin 2, and Centrin 3 participate in this process, FOR20 and Centrin 2 being involved in the assembly of the transition zone. We investigated the function of two …

Basal Body Positioning and Anchoring in the Multiciliated Cell Paramecium Tetraurelia: Roles of OFD1 and VFL3 Read More »

Acute Transcriptional Up-regulation Specific to Osteoblasts/Osteoclasts in Medaka Fish Immediately after Exposure to Microgravity

Bone loss is a serious problem in spaceflight; however, the initial action of microgravity has not been identified. To examine this action, we performed live-imaging of animals during a space mission followed by transcriptome analysis using medaka transgenic lines expressing osteoblast and osteoclastspecific promoter-driven GFP and DsRed. In live-imaging for osteoblasts, the intensity of osterix- …

Acute Transcriptional Up-regulation Specific to Osteoblasts/Osteoclasts in Medaka Fish Immediately after Exposure to Microgravity Read More »

How to Conduct Localized Proteomics of Microscopic Regions

This webinar is about a recently developed technique that allows localized proteomics of microscopic regions of interest, such as specific cell types or neuropathological features of disease. This technique uses laser capture microdissection (LCM) to isolate regions/cells of interest followed by label-free quantitative mass spectrometry (LC-MS) and has been optimized to use formalin-fixed paraffin embedded (FFPE) …

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Coupling of vinculin to F-actin requires Syndecan-4 proteoglycan

Heparan Sulfate Proteoglycans act as a cell surface co-receptors for many proteins in which a signal is sent downstream via its cytosolic domain. The role of syndecan-4 proteoglycans in FA assembly was studied in endothelial cells, and single molecule localization super-resolution microscopy showed that Syn4 loss altered the cytoskeleton protein network assembly. Using molecular and …

Coupling of vinculin to F-actin requires Syndecan-4 proteoglycan Read More »