Month: November 2015

Color Infidelity: Why Using a Light Source Incorrectly is Cheating on your Data

Whether you are capturing an image of a beetle carapace or attempting to document a mission critical pathology slide, color matters. There are many influences on color in the imaging process including lighting, optics, sensor, and monitor, and ultimately print. The first, and generally most important, is lighting. The solution is not as simple as …

Color Infidelity: Why Using a Light Source Incorrectly is Cheating on your Data Read More »

Cross-strand Binding of TFAM to a Single mtDNA Molecule Forms the Mitochondrial Nucleoid

Scientists from the Max Planck Institute for Biology of Ageing (MPI AGE) in Cologne, the Max Planck Institute of Biophysics (MPI BP) in Frankfurt a.M., and the Max Planck Institute for Biophysical Chemistry (MPI BPC) in Göttingen have gained fundamental insights into the organization of mitochondrial DNA (mtDNA). The researchers observed in high-resolution images gained …

Cross-strand Binding of TFAM to a Single mtDNA Molecule Forms the Mitochondrial Nucleoid Read More »

The Value of Intraoperative OCT Imaging in Vitreoretinal Surgery

The role of iOCT in vitreoretinal surgery continues to be defined by active research and enhancements to integrative technologies. Further research is needed to better define the specific applications of iOCT that impact patient outcomes and surgical decision-making. Future advancements in integrative systems, OCT-friendly instrumentation, and software algorithms will further expand the horizon of iOCT …

The Value of Intraoperative OCT Imaging in Vitreoretinal Surgery Read More »

Handheld Optical Coherence Tomography During Sedation in Young Children With Optic Pathway Gliomas

Importance: Monitoring young children with optic pathway gliomas (OPGs) for visual deterioration can be difficult owing to age-related noncompliance. Optical coherence tomography (OCT) measures of retinal nerve fiber layer (RNFL) thickness have been proposed as a surrogate marker of vision but this technique is also limited by patient cooperation. Objective: To determine whether measures of …

Handheld Optical Coherence Tomography During Sedation in Young Children With Optic Pathway Gliomas Read More »

High Resolution Optical Coherence Tomography Guided Donor Tissue Preparation for Descemet’s Membrane Endothelial Keratoplasty Using Reverse Big Bubble Technique

Purpose: To assess the feasibility of High Resolution Spectral Domain Optical Coherence Tomography (HR-SDOCT) to guide donor tissue preparation in Descemet’s Membrane Endothelial Keratoplasty (DMEK) using the reverse big bubble technique. Methods: Three corneo-scleral discs were included in this ex-vivo experimental study. A 27 gauge cannula was introduced into each cornea at the periphery by …

High Resolution Optical Coherence Tomography Guided Donor Tissue Preparation for Descemet’s Membrane Endothelial Keratoplasty Using Reverse Big Bubble Technique Read More »

OCT Publication List

High-Resolution Optical Coherence Tomography–Guided Donor Tissue Preparation for Descemet Membrane Endothelial Keratoplasty Using the Reverse Big Bubble TechniqueCabot, Florence; Kankariya, Vardhaman P; Ruggeri, Marco; Yoo, Sonia H; Vaddavalli, Pravin K; Parel, Jean-Marie; Kymionis, George DCornea. 2014 Apr; 33(4): 428–431 doi:  10.1097/ICO.0000000000000070 Ganglion Cell Layer–Inner Plexiform Layer Thickness and Vision Loss in Young Children With Optic …

OCT Publication List Read More »

Intraoperative OCT Today and Tomorrow: The PIONEER Study Two-year Results and Beyond

Over the last years, Optical Coherence Tomography (OCT) has become a potential real-time surgical assistive device. Numerous vitreoretinal surgical conditions have been described in the literature, including macular holes, epiretinal membranes, retinal detachments, vitreomacular traction, and retinopathy of prematurity. The high-resolution, cross sectional information provided by iOCT creates a unique feedback system for vitreoretinal surgery. …

Intraoperative OCT Today and Tomorrow: The PIONEER Study Two-year Results and Beyond Read More »

Video Talk by Sonia H. Yoo: Interoperative OCT Imaging of Selective Lamellar Keratoplasty

The work prepared and presented within this video demonstrates preliminary research, and the promising future of perioperative OCT to aid the diagnosis of physiological and pathological conditions during ophthalmic surgery in order to help guide surgical decision making in anterior segment cases. Showing SDOCT Images acquired with an Envisu SD-OCT system, Prof. Yoo demonstrates the …

Video Talk by Sonia H. Yoo: Interoperative OCT Imaging of Selective Lamellar Keratoplasty Read More »

Video: Traumatic Soft and Hard Tissue Wound on the Maxillary Anterior with Microscope Assisted Rehabilitation

The concept of minimal intervention dentistry became a primary approach to treat carious lesions. These days, this concept could be adapted to manage soft tissue around the teeth and implants as a minimally invasive technique. “Using Leica microscopes, this minimally invasive technique helps to achieve satisfying esthetic results as well as best health outcomes which …

Video: Traumatic Soft and Hard Tissue Wound on the Maxillary Anterior with Microscope Assisted Rehabilitation Read More »