Month: September 2014

Defect Transport Mechanism Leads to Shortened Chromosome Ends

Scientists at the University of Göttingen have deciphered the biogenesis of an enzyme complex whose role is to ensure that the ends of chromosomes are not shortened during the cell division process and that the genetic material is fully maintained. To be fully functional, telomerase RNA has to be shuttled in and out of the …

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Brief Introduction to Specimen Trimming

For instance, to achieve the optimum sectioning results of biological embedded samples, the surrounding embedding material has to be entirely removed. Thus, only the sample is present in the block-face and a “homogeneous” material can be sectioned. Especially when sectioning with a glass knife, the embedding material would influence the section results due to the …

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Clearing Procedures for Deep Tissue Imaging

In his book, Spalteholz used the term “das Durchsichtigmachen” – a strange word, even for Germans. It is more specific than “clearing” as it literally means “pellucidation” i.e “make transparent” – of course without destroying the spatial structure. To achieve this goal by an entirely different approach, the group of Karl Deisseroth set out to …

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Are Your Digital Microscope Measurements Accurate and Reliable?

For certain applications, such as the production and maintenance of automobiles, aircraft, or power plants, quality control and reliability assurance, as well as safety and health inspection, accurate and reliable image data with precise calibration are very important. Digital microscopes, i.e. microscopes with no eyepieces and a digital camera detector, are appealing for a wide …

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Glycerol Spraying/Platinum Low Angle Rotary Shadowing of DNA with the Leica EM ACE600 e-beam

Prior to the experiment, both the Pt/C and the C gun were cleaned thoroughly, the targets and the filaments were set up according to the manual. The Pt/C gun was mounted at the right port of the vacuum chamber, the C gun at the left side. The instrument was set up with the LARS (low …

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Lifelog application and smartwear products / Stories / Sony Design / Sony

Life-enriching technology that’s a perfect fit We set out to make smartwear products more familiar. Technology that helps you to be who you are, or who you’d like to be. Next-gen smartwear products soon feel like an extension of your body and mind. Making technology more intimate, more familiar People turn to technology as an …

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