Month: October 2013

Xperia™ Z1 Smartphone / Stories / Sony Design / Sony

Putting it all together for smartphonesas you’ve never experienced them before The Xperia Z1 brought together many contributors across Sony. Craftsmanship in design and technology created a fresh user experience—taking Xperia another step forward. Concept 〈 Xperia Z1 〉 A convergence of Sony technology Sony has a history of creating a diverse range of products: …

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Rapid Immunohistochemical Diagnosis of Tobacco Mosaic Virus Disease by Microwave-assisted Plant Sample Preparation

Immunoelectron microscopy is a powerful method to diagnose viral diseases and to study the distribution of the viral agent within plant cells and tissues. Nevertheless, current protocols for the immunological detection of viral diseases with transmission electron microscopy (TEM) in plants take between 3 and 6 days and are therefore not suited for rapid diagnosis of …

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Patch Clamp Recordings from Embryonic Zebrafish Mauthner Cells

Mauthner cells (M-cells) are large reticulospinal neurons located in the hindbrain of teleost fish. They are key neurons involved in a characteristic behavior known as the C-start or escape response that occurs when the organism perceives a threat. The M-cell has been extensively studied in adult goldfish where it has been shown to receive a …

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Nobel Prize 2013 in Physiology or Medicine for Discoveries of the Machinery Regulating Vesicle Traffic

The three Nobel Laureates have discovered a fundamental process in cell physiology. These discoveries have had a major impact on our understanding of how cargo is delivered with timing and precision within and outside the cell.  Vesicle transport and fusion operate, with the same general principles, in organisms as different as yeast and man. The …

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Thermodynamic Considerations Regarding the LN2 in a High Pressure Freezer

Employing liquid nitrogen (LN2) as a coolant in the complex process of high pressure freezing raises certain considerations regarding phase transition not only of the liquid sample to be frozen but also of the element used to freeze the sample. According to the phase diagram of nitrogen, changes in temperature or pressure will alter the …

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Interview with Stefan Hell: Breaking Nanoscale Boundaries

Stefan Hell is credited with having conceived and applied the first viable concept for breaking Abbe’s diffraction limit in a light-focusing microscope. He is a scientific member of the Max Planck Society and a director at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany, where he currently leads the department of nanobiophotonics. Peter …

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A Flip of the Mitotic Spindle has Disastrous Consequences for Epithelial Cells

“The findings derived from epithelial biology often lead to a better understanding of cancer development”, says Nakajima.”We have found that spindle orientation has a tumor-suppressive role in proliferating epithelia. So we are looking for other spindle regulators that may represent novel tumor suppressors.” Human epithelial cells do express mammalian Scribble and Discs large proteins, and …

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Brief Introduction to Contrasting for EM Sample Preparation

Fixatives Osmium tetroxide fixative enhances the contrast. It acts as fixative as well as enhancer of contrast during post-staining by interacting with uranyl acetate and lead citrate.It has been indicated that fixation time has an effect on contrast obtained by uranyl acetate contrasting. A long fixation with Osmium tetroxide decreases e.g. the contrast of chromatin. …

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Higher Motivation, Longer Concentration – Ergonomics as a Competitive Advantage

Sensor and identification technology, industrial cameras: when top precision is required, the name Baumer Electric is soon mentioned. The Swiss company designs and produces components for manufacturing facilities all over the world. To be able to guarantee that the finished components are of the highest possible quality, elaborate quality inspections are carried out part for …

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