Month: March 2013

Intravital Immunofluorescence for Visualizing the Microcirculatory and Immune Microenvironments in the Mouse Ear Dermis

This method should be interesting and useful to the scientific community, particularly in the areas of microcirculation, immunology and tumor microenvironment including studies on tumor angiogenesis and anti-angiogenic therapy. It has some advantages over other intravital imaging techniques: (i) Intravital fluorescence imaging has been used in microcirculation studies, e.g., to track solute leakage from blood …

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Targeting of Peroxisomal Matrix Proteins in the Diatom Phaeodactylum Tricornutum

Peroxisomes are single membrane bound compartments. They are thought to be present in almost all eukaryotic cells, although the bulk of our knowledge about peroxisomes has been generated from only a handful of model organisms. Peroxisomal matrix proteins are synthesized cytosolically and posttranslationally imported into the peroxisomal matrix. The import is generally thought to be …

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