Month: August 2008

The First Supercontinuum Confocal that Adapts to the Sample

A common challenge with multiparameter fluorescence is that excitation even by a narrow line will excite not only the targeted dye, but also other dyes in the sample. In most cases this is not wanted as the separation of various channels suffers from cross excitation making some applications, like FRET experiments, difficult to work with. …

The First Supercontinuum Confocal that Adapts to the Sample Read More »

From Molecules to Tissues

Oncological research has been deeply involved in this change process, recognising the risks of a sterile approach based solely on in vitro models. The need for therapies targeting specific molecules realises a trait d’union starting from analysis of single molecule biochemical structures and extending to their role in the cellular environment both at intra and …

From Molecules to Tissues Read More »

Obese and Slim Yeast Cells

Besides molecular-biological, genomic and proteomic techniques, high-resolution light microscopy is important for gaining innovative insights into cellular lipid synthesis, lipid and membrane dynamics and morphological changes in connection with lipid metabolism disorders. With its diameter of 5–8 μm, the yeast cell used to be considered an unsuitable specimen for light microscopic examination. Actually, the technological …

Obese and Slim Yeast Cells Read More »

Forensic Detection of Sperm from Sexual Assault Evidence

Forensic laboratory personnel are well aware that the entire structure of DNA profiling begins with the identification of a questioned stain from an article of evidence or from the analysis of an evidence swab. There are both criminalistic and laboratory procedural reasons to identify the source of the biological material that will be processed for …

Forensic Detection of Sperm from Sexual Assault Evidence Read More »